REG-001 is a novel small-molecule antidote to organophosphate poisoning designed to protect against exposure to various types of nerve agents.

Murine and Non-Human Primate models have shown REG-001 to be highly effective, minimally toxic, and able to cross the blood brain barrier (BBB) to treat any immediate organophosphate toxicity throughout the brain and body while preventing the persisting seizures that recur following exposure.